Behçet’s disease

Behçet’s Syndrome is one of the rare non-communicable diseases, most of the cases of which are concentrated in Turkey. On the other hand, we find that there is one infection for every 170,000 people in the United States, and it is worth noting that this disease is an autoimmune disease that affects the blood vessels in the human body,[1] This disease is accompanied by infections in different areas of the body. This inflammation can affect the retina, the brain, the joints, the skin, or even the intestines.[2]

Symptoms of Behcet’s disease

The patient with Behçet’s disease goes through periods in which the symptoms of the disease intensify, and other periods in which the symptoms disappear and the patient’s condition improves, and the symptoms of this disease vary according to the part of the body affected by inflammation.[3]

  • Oral ulcers: Oral ulcers are one of the most common symptoms among people with Behçet’s disease, and these ulcers appear on the tongue, lips, the inside of the mouth, and the gums. Leaves no traces or marks.
  • Genital ulcers: They are one of the common symptoms that appear on people with Behçet’s disease, as genital ulcers appear similar to oral ulcers, and once these ulcers recover, they leave behind scars and traces in many cases. These ulcers can also cause swelling and inflammation of the testicles in men. While it may cause severe pain in women during intercourse, it is worth noting that these genital ulcers are not contagious, and are not transmitted from one person to another through sex.
  • Skin infections: Behcet’s disease may cause skin problems in many patients. As the appearance of abnormal skin lesions, swollen and reddened nodules called Erythema nodosum may appear on the feet that may leave permanent traces after they recover, in addition, acne-like grains may spread in the body in what is known as pseudofolliculitis (English: Pseudofolliculitis).
  • Arthritis: About two-thirds of people with Behçet’s disease have symptoms similar to those of arthritis, where the joints are swollen, stiff, and the patient suffers from pain and discomfort when moving, and this inflammation usually affects the knee, ankle, wrist, and small joints in the hands, and often The damage that Behçet’s disease causes to the joints is not permanent, and therefore the symptoms that appear on the patient can be effectively controlled.
  • Inflammation of the eyes: Approximately 50% of people with Behçet’s syndrome suffer from eye inflammation, which often occurs suddenly, and uveitis is the most common eye infection, which leads to redness of the eyes, blurred vision, and the appearance of floating objects (in English: Floaters) in the eye, and in severe and rare cases, the patient may be blind and lose his sight.
  • Skin sensitivity: In some cases, the skin becomes sensitive to any injury or wound, for example, when a needle is inserted into the patient’s skin, this may cause the appearance of a tumor or a large reddish scar around the area where the needle was inserted.
  • Gastroenteritis: The stomach and intestines can be affected by inflammation, which may lead to loss of appetite, severe diarrhea with blood, indigestion, nausea, and vomiting.
  • Blood clotting: Inflammation of the walls lining the blood vessels can lead to blood clotting, such as deep vein thrombosis, which usually affects the veins in the legs, and requires immediate medical intervention to get rid of this clot.
  • Aneurysm: The blood vessels expand as a result of inflammation that helped weaken their walls and swell, and usually the patient does not show any symptoms until these vessels expand enough to put pressure on the surrounding parts, or rupture leaving the patient suffering from internal bleeding, and the symptoms that appear vary. At that time, the patient must then vary the location of the aneurysm, and these symptoms include feeling pain in the extremities, suffering from sudden headaches, dizziness, shortness of breath, and in some cases the patient’s awareness may be disturbed and he loses consciousness.
  • Inflammation of the nervous system: It can be said that inflammation of the central nervous system causes the appearance of the most serious symptoms of Behçet’s disease. The patient has severe and rapidly developing symptoms, such as headaches, double vision, loss of balance, changes in behavior or personality, convulsive seizures, in addition to partial paralysis. on one side of the body.

Factors that increase the risk of developing Behcet’s disease

There are several factors that increase the risk of developing Behcet’s disease, including the following:[4]

  • Age: Behçet’s disease affects individuals at any age, but it most often affects them in their twenties or thirties.
  • Where to live: People who live in regions of the Far East and the Middle East, including Turkey, Iran and China, have a higher risk of developing Behcet’s disease.
  • Gender: Behçet’s disease is more common among males than among females.
  • Genes: The presence of certain genes in some people’s bodies may increase their risk of developing Behcet’s disease.

Behçet’s disease treatment

The doctor advises the patient about some changes that should be made in his lifestyle, such as rest and exercise, and prescribes some drug treatments, including the following:[1]

  • Topical treatments: in order to relieve symptoms in the affected area, such as the use of topical corticosteroids that come in many pharmaceutical forms such as eye drops, lotions, and ointments that are applied to the site of the injury, and examples of which are; Triamcinolone acetonide, betamethasone, and dexamethasone.
  • Oral treatments: It may be necessary to use some medications that are taken orally in treatment, including the following:
  • Colchicine.
  • Corticosteroids.
  • Medicines that affect the immune system in one of two ways:
  • It suppresses the immune system such as; Azathioprine, cyclosporine, and cyclophosphamide.
  • It works by changing the way the immune system works in the body.

the reviewer

  1. ^ AB Lori Smith (19-5-2016), “What is Behcet’s disease?”, www.medicalnewstoday.com, Retrieved 20-4-2018. Edited.
  2. ↑ William C. Shiel (19-8-2016), “Behcet’s Syndrome: Symptoms, Diet, & Treatment”, www.medicinenet.com, Retrieved 20-4-2018. Edited.
  3. ↑ “Behçet’s disease”, www.nhs.uk, 11-23-2016, Retrieved 20-4-2018. Edited.
  4. ↑ “Behcet’s disease”, www.mayoclinic.org, 7/29/2017, Retrieved 20-4-2018. Edited.

What is Behçet’s disease?

writing – on the date : – Last updated: 2022-06-08 12:30:01