Grapes are one of the types of fruits that have been cultivated for thousands of years, and are available in different types, including green, red, black, yellow, and pink grapes. In temperate climates around the world, grapes provide a range of health benefits due to their high content of nutrients and antioxidants which are found in higher concentration in the outer skin and seeds, which is why most research on grapes is done using extracts from the seeds or the outer skin.[1]

Grape seed benefits

Grape seed contains very high amounts of various antioxidants, and grape seed extract made from ground and dried grape seeds is a form of nutritional supplement, and therefore it contains very high concentrations of nutrients, and we mention the benefits of this extract as follows:[2]

  • Lowering blood pressure: Several studies have found that grape seed extract has an effect on high blood pressure, and the results showed that it significantly lowers systolic and diastolic blood pressure.
  • Improving blood flow: Some studies suggest that grape seed extract can improve blood flow and circulation, by thinning the blood, reducing the risk of blood clots.
  • Reducing the risk of heart disease: Grape seeds can help reduce the oxidation of bad cholesterol (LDL), which is one of the risk factors for heart disease and atherosclerosis, and it also reduces the oxidation of heart tissue and arteries as a result of exposure to stress.
  • Improving collagen and bone strength: Increased consumption of flavonoids helps improve the process of collagen and bone formation, and grape seed extract is a rich source of this compound, and many animal studies have shown its ability to increase bone strength and density, and relieve pain. And the loss of bone and cartilage in cases of osteoporosis, but these benefits need more studies to prove their effectiveness in humans.
  • Maintaining brain health: The flavonoids present in grape seed extract help delay or reduce the risk of developing neurodegenerative diseases, such as Alzheimer’s, in addition to improving cognitive status, and preventing memory loss, as a result of its antioxidant and anti-inflammatory properties, but these benefits need to be addressed. More human studies to prove its efficacy.
  • Improving kidney function: grape seeds can reduce the risk of kidney damage, improve their health, and their ability to perform their functions; This is done by reducing oxidative stress and its damage caused by inflammation in the kidneys.
  • Inhibiting the growth of infection-causing microbes: Grape seed has anti-bacterial and anti-fungal properties, and several studies have shown its ability to inhibit the growth of antibiotic-resistant, common disease-causing bacterial strains, and prevent food-borne bacterial diseases.
  • Reducing the risk of cancer: A high intake of antioxidants such as flavonoids and proanthocyanidins is associated with a reduced risk of various types of cancer. Several laboratory studies have shown the strong ability of grape seed extract to inhibit the formation of cancer cells in the breast and lung. stomach, liver, prostate, and pancreas, but this benefit needs more human studies to prove its effectiveness.
  • Liver health: Grape seed can protect the liver from drug-induced toxicity and damage, however, more human studies are needed to prove this benefit.
  • Wound healing: Creams containing grape seed extract can contribute to wound healing. And that by stimulating the secretion of growth factors in the skin, so it can be considered an effective treatment for wound healing.

Grape seed side effects and warnings

Eating grapes with their seeds is considered safe, and taking grape seed extract is generally safe, but it can cause a range of side effects, and we mention from the damages of grape seed extract and the warnings of its use as follows:[3]

  • It can cause headaches, itching of the scalp, dizziness, and nausea.
  • People allergic to grapes should avoid using grape seed extract.
  • For people with bleeding disorders or high blood pressure, as well as for people who take any type of medication regularly, consult a doctor before starting to use grape seed extract. This extract can interfere with blood-thinning medications, non-steroidal anti-inflammatory pain relievers such as aspirin, some heart medications, and cancer medications, among others.
  • It is recommended to avoid the use of grape seed extract in children, pregnant women, and breastfeeding women, due to the lack of sufficient evidence about its safety for these groups.

Grape seed oil benefits

The oil extracted from grape seeds has a range of health benefits, and the following is an explanation of some of these benefits:[4]

  • It is a good source of vitamin E, which has antioxidant properties, which in turn protect cells from free radical damage, the high of which is linked to cancer, heart disease, and other chronic diseases.
  • Contributes to maintaining healthy skin; By moisturizing the skin, reducing acne, tightening pores, and reducing the appearance of scars, this oil is characterized by the ability of the skin to absorb it quickly, and it does not clog pores, and therefore it is suitable for all skin types.
  • It contributes to improving the health of the hair and scalp, getting rid of dead skin, moisturizing it, and thus relieving dry dandruff, and its use does not cause an increase in hair greasy.
  • Its use in combination with aromatherapy helps relieve stress and anxiety.

the reviewer

  1. ↑ Melissa Groves (2018-8-22), “Top 12 Health Benefits of Eating Grapes”,, Retrieved 26-11-2018. Edited.
  2. ↑ Caroline Hill (7-10-2018), “10 Benefits of Grape Seed Extract, Based on Science”,, Retrieved 26-11-2018. Edited.
  3. ↑ “Grape Seed Extract”,, Retrieved 27-11-2018. Edited.
  4. ↑ Peggy Pletcher (2016-7-20), “The Health and Beauty Benefits of Grapeseed Oil”,, Retrieved 27-11-2018. Edited.

What are the benefits of grape seeds?

writing – on the date : – Last updated: 2022-06-22 15:03:01