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Monday February 24, 2020

Study: Intestinal bacteria linked to arterial pulmonary hypertension

Researchers have identified a distinct group of bacteria in the gut that may contribute to predicting pulmonary arterial hypertension (PAH), according to new research published today in the American journal Hypertension.

According to the American medical site “HealthDayNews”, the researchers said that “PAH” is a chronic and progressive disease in which the arteries that supply blood to the lungs are narrow or blocked, which leads to symptoms such as shortness of breath, heart palpitations, fatigue and others.

People with “PAH” have persistent high blood pressure in the arteries of the lungs causing the right side of the heart to work with a very large effort to pump blood, which leads to heart failure on the right side, which is much less common than systemic blood pressure, which represents blood strength Moving through the blood vessels throughout the entire body.

Each person has a group of bacteria in their intestines – known as “microscopic bacteria” – that aid in digestion, the researchers said, noting that the presence of certain “microbiota” bacteria in their intestines predicted the presence of pulmonary arterial hypertension (PAH) with an accuracy of 83%.

“We have shown for the first time that there are certain bacteria in the intestine found in people with pulmonary arterial hypertension (PAH),” said Mohan Raizada, lead author of the study and distinguished professor in the Department of Physiology and Functional Genomics at the University of Florida School of Medicine in Florida. ), While current PAH treatments focus on the lungs, looking at the axis of the lung and intestine together may open the door to new treatments centered in the digestive system. ”

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To confirm the results of the study, stool samples were collected from 18 patients with pulmonary arterial hypertension (PAH) and 12 people without a history of heart and lung disease. Microbial DNA was isolated from stool samples and their sequence. The test revealed a group of unique bacteria in PAH patients That is associated with pulmonary arterial hypertension (PAH).

However, this is not the first time that intestinal bacteria have been linked to medical conditions, as a variety of different features of microscopic diseases have been linked to a variety of cardiovascular diseases including high blood pressure.

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