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Orphenadrine(Orphenadrine) The muscle relaxant most commonly used by physical therapists to relieve pain. Get to know this drug closely, a detailed explanation of how to use it correctly, tips before using the drug, contraindications to the use of the drug, its price in the Arab and foreign markets, and a lot of valuable information about it.

What is Orphenadrine?

It is a medicine used to treat musculoskeletal pain caused by a strain, sprain or other injury. This medicine is used by physiotherapists in many physiotherapy sessions, however this treatment does not replace the use of other treatments recommended by the doctor, nor does it replace rest and physiotherapy sessions. This medicine affects the central nervous system, making the patient feel comfortable.

Generic name of the drug orphenadrine.
Brand Names Antiflex, Norflex, Flexoject, Banflex, Orphenate, Flexon

Mio-Rel, Myolin, Norflex, Orfro Injectable

drug classification Muscle stretcher.
Pharmaceutical Forms Swallowing tablets, Swallowing extended-release tablets, Injection.
drug manufacturer novartis.

Indications for use of orphenadrine

Indications for use of orphenadrine
Indications for use of orphenadrine

This medication is used to relieve muscle spasms as a result of injury or excessive stress, as it acts as a muscle relaxant, which reduces pain and increases comfort, especially when the patient performs physical therapy sessions and adheres to the doctor’s instructions for comfort.

Contraindications to the use of orphenadrine

This medicine is contraindicated in some patients and in some cases such as:

  • If the patient is allergic to orphenadrine, which is the active substance of the drug.
  • A patient who has problems urinating.
  • If the patient has been diagnosed with myasthenia gravis.
  • A patient who suffers from an enlarged prostate.
  • Glaucoma patient.
  • If the patient complains of a stomach ulcer, or a blockage in the digestive system.
  • A patient who complains of difficulty swallowing.
  • It is forbidden to take the medicine for patients under the age of 18 years.
  • The medicine should not be used in elderly patients over 65 years of age.

Read also: Hydromorphone

Important tips before taking orphenadrine

There are some tips that the patient needs to know and adhere to with the drug, which are:

  1. The patient must adhere to the doses and instructions recommended by the doctor.
  2. If the patient is on this list, the doctor must be told before starting the medication:
    • He suffers from heart disease.
    • If the patient is using an anesthetic drug.
    • He has a heart rhythm disorder.
    • A person with coronary heart disease.
    • He suffers from any chronic diseases.
  3. A woman who is taking this medicine should tell her doctor if she becomes pregnant while taking this medicine.
  4. Adhere to physical therapy sessions and rest with medication; to get the desired result.
  5. It is necessary to tell the dentist or surgeon about this medicine, in case the patient needs to visit either of them.

pregnancy and breastfeeding

Because the studies conducted on pregnant and lactating women using this drug are insufficient, the woman to whom the doctor recommends this medicine must tell him if she is pregnant or breastfeeding before taking it; So that he can weigh the benefits and harms in this case.

Read also: AndroGel

How to take orphenadrine

How to take orphenadrine
How to take orphenadrine

The medicine can be taken correctly by following the following instructions:

  • Especially the elderly and children, this medicine should not be taken in more amounts than prescribed by the doctor.
  • Your doctor will usually recommend taking the medication twice a day. Follow your doctor’s instructions for dosing.
  • Do not share this medicine with any other patient without consulting a doctor.
  • This medicine should not be given to a patient if he has a history of drug abuse or addiction.
  • The extended-release tablets should not be broken or crushed before swallowing, and they should be swallowed whole.
  • Take the treatment at the appointed time; To ensure the result and improve the state of health.
  • You must tell the doctor if you take the medicine and do not notice any improvement in symptoms, or relief in pain.
  • This medicine can be taken with or without food, and follow the directions prescribed by your doctor.

Read also: Mirabegron

Recommended doses for this drug

The recommended adult dose of this medicine is as follows, based on the pharmaceutical form of treatment:

  • Extended-release tablets: The dose is 100 mg, or one tablet, twice a day, to be taken orally.
  • Recommended parenteral dose: 60 mg every 12 hours, to be taken IM or IV, as appropriate for the patient.

What do you do if you forget to take a dose?

The patient can take the forgotten dose if he remembers it immediately in the event that there is an interval between it and the next, or skip it if there is no time interval between the two doses, and in both cases the doses should not be doubled for any reason.

What do you do if you take an overdose?

There is no need to worry if the patient takes an overdose, he can contact his doctor in this case, or go to the nearest hospital and seek help.

Actions to avoid while taking this medicine

The patient should be careful not to do any activities that require a presence of mind, such as driving a car or using sharp tools, even experiencing the effect of the drug on it.

Read also: Myrbetriq

Orphenadrine side effects

The most common side effects with this medicine are:

  • The appearance of allergic reactions as a result of the patient’s sensitivity to the drug, such as: swelling of the throat and lips, difficulty breathing.
  • Urinary retention.
  • pain with urination;
  • a heart rhythm disorder;
  • Feeling anxious or confused.
  • hallucinations;
  • Dry mouth.
  • Nausea and vomiting.
  • dizziness, drowsiness;
  • constipation;

This is a list of the most common side effects with this drug and not to list them, so the patient must tell the doctor if any of these side effects appear, or if other side effects appear to see how he can deal with them.

The 5 drugs that interact with orphenadrine

There are many drugs that can interact with this drug. Therefore, the patient must update his list of medicines, and present it to the doctor before he prescribes this treatment, provided that this list contains all prescribed and non-prescribed medicines, vitamins and herbs. It should also contain all medicines listed under the name:

  1. Sleeping pills (Hypnotic).
  2. Anxiety and depression medications.
  3. other muscle extensors.
  4. Narcotic drugs.
  5. Cough medicines.

Alternative medicine to orphenadrine

Alternative medicine to orphenadrine
Alternative medicines for Orphenadrine

The most famous alternatives that can be used instead of orphenadrine after referring to the doctor:

  1. Norflex.
  2. Banflex.
  3. orphenadrine;
  4. Flexject medication.
  5. Flexon.
  6. Antiphilix.

Orphenadrine price in the market

The price of Orphenadrine Plus 20 tablets in Egypt is 8 Egyptian pounds, while the cost of the alternative medicine known as Norflex, which is available in a concentration of 100 mg, is about 2.38 Kuwaiti dinars. As for the price of treatment internationally, the cost of the extended-release tablets in a concentration of 100 mg is about 22 dollars.

Frequently Asked Questions About Orphenadrine

How should orphenadrine be stored correctly?

The patient can keep the medicine at home on a high shelf away from children’s hands, and away from moisture and sunlight.

What concentrations of orphenadrine tablets and injections are available?

The concentration of the tablets is 100 mg, whether they are extended-release or regular, and the concentration of injections available is 30 mg per ml.

Why shouldn’t the extended-release pills be broken when swallowed?

The patient should not break this pill before swallowing it; Because this leads to the release of all the active substance in the pill at once, and thus increases the risk of side effects resulting from it.

In the end, Orphenadrine is one of the most popular treatments used as a muscle relaxant and pain reliever. This medicine should be used according to the doctor’s instructions, with adherence to the prescribed doses. To avoid the appearance of side effects, especially with elderly patients and children under the age of 18, and there is no need to worry about side effects, because if they appear, all the patient has to do is go to the hospital.