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Nucenta medicine (Nucynta), Nucinta is a medicine that relieves severe and moderate pain. It belongs to a class of medicines called opioid pain relievers. Nucinta is available by prescription for adults over 18 years of age.

What is Nucynta?

It is the brand name of tapentadol, which is classified under the category of narcotic analgesics. It is used to relieve severe to moderate pain after surgery or after severe injuries, if weaker pain relievers are not effective.

Generic name of the drug Tapentadol
Brand Names Nucynta -palexia – Duovolt – Tapal – Tapcynta
drug classification Narcotic analgesics
Pharmaceutical Forms Immediate-release oral tablets – extended-release oral tablets
drug manufacturer Johnson & Johnson

Reasons for using Nucenta

Reasons for using Nucenta
Reasons for using Nucenta

The proper diagnosis of any disease condition determines the type of drug, its dose and the way it is used. The reasons for using Nucenta are:

  • Tapentadol is used to help relieve moderate to severe pain such as pain from injuries.
  • The medicine can be used to treat and relieve postoperative pain.

Contraindications to the use of Nucenta

Tapentadol should be avoided in the following cases:

  • Cases of severe constipation.
  • If you are breastfeeding or pregnant.
  • If you suffer from asthma or chronic obstructive pulmonary disease.
  • If you suffer from inflammatory bowel problem.
  • Problems with the thyroid, adrenal glands, gallbladder, or pancreas.
  • Having an allergic reaction to the active substance tapentadol.
  • If you suffer from liver or kidney disease problems.
  • Brain tumors or head injuries.
  • epileptic seizures;
  • Muscle weakness conditions such as myasthenia gravis.
  • Prostate problems and difficulty urinating.
  • If you have taken any MAO inhibitor medicines in the previous two weeks, such as:
    • linezolid;
    • Methylene blue injection.
    • isocarboxazid;
    • phenelzine;
    • tranylcypromine.

Important tips before taking Tapentadol

Before taking tapentadol, you should follow the following tips:

  • Do not take Nucynta in larger amounts than your doctor has prescribed for you, or for longer.
  • Do not crush or break the tablets before taking them, as you may be exposed to a life-threatening concentrated dose.
  • Avoid driving a car while taking this medicine.
  • Keep tapentadol in a safe place and do not share it with anyone.
  • Avoid alcoholic beverages.

pregnancy and breastfeeding

You should tell your doctor if you are pregnant. Tapentadol may cause life-threatening withdrawal symptoms in the baby after birth, if the mother took Nucynta during pregnancy, and it is not recommended for use during delivery, it may cause difficulty breathing in the baby after birth as well.

It is not yet known if tapentadol passes into breast milk, so check with your doctor before using Nucynta if you are breastfeeding, and if you notice extreme drowsiness or slow breathing in a baby.

Read also: Micapsa

How to take Nucynta

How to take Nucenta
How to take Nucenta

There are some instructions that must be followed on how to take the medicine and they are as follows:

  1. Before taking the medication, read the attached medication guide.
  2. The medicine is taken orally and as directed by the doctor.
  3. You can take Nucynta with a full glass of water at the same times each day, with or without food.
  4. You must stop taking any medicine that contains the active ingredient tapentadol.
  5. Take Nucenta with food if you have nausea.
  6. It is preferable to consult a doctor about ways to reduce nausea, such as lying down for one to two hours.
  7. Do not increase your prescribed dose or for longer than the prescribed dose.
  8. tapentadol works best if it’s used before the pain gets worse, and it’s not prescribed to take it when needed.
  9. Do not crush or break a Nucynta extended-release tablet. Swallow it whole to avoid serious side effects.

Do not stop using Nucynta suddenly, but ask your doctor before stopping the medication so that you do not experience withdrawal symptoms

Nucenta doses

The dosage of the drug depends on the medical condition and the degree of response to treatment. Dosages are divided into:

  • Usual Adult Dose for Pain from the immediate-release oral tablet:
    • Initial dose of 50 to 100 mg orally every 4 to 6 hours, depending on pain.
    • A second dose may be given 1 hour after the first dose if needed on the first day.
    • Subsequent doses of 50, 75 or 100 mg every 4 to 6 hours.
    • As for the maximum dose, it is given 700 mg on the first day and then 600 mg per day on the following days.
  • Usual adult dose for pain from the extended-release oral tablet:
    • Initial dose of 50 mg orally twice daily.
    • Dosage increases should not exceed 50 mg twice daily every 3 days.
    • Regular fixed dose of 100 mg to 250 mg orally twice daily.
    • Maximum dose: 500 mg daily.

What do you do if you forget to take a dose?

Because tapentadol is used to relieve pain, you should not miss a dose, but you should skip a missed dose if it is time for your next scheduled dose. Do not take other medicines to make up for the forgotten dose. Do not take more than the prescribed dose in 24 hours.

What do you do if you take an overdose?

If you take an overdose, call an emergency department or call a poison help line. A tapentadol overdose can be fatal, especially in children or people taking Nucynta without a prescription. Symptoms of an overdose include:

  • severe drowsiness;
  • muscle weakness;
  • slow breathing and heart rate;
  • Cold and wet skin.
  • Fainting, or coma.

Read also: Mucinex

Actions to avoid while taking this medicine

What you should avoid while taking tapentadol are the following:

  • Avoid sharing the medicine with others to avoid misuse of the medicine.
  • Do not stop taking the medicine suddenly so that you do not experience withdrawal symptoms.
  • Avoid driving a car while taking Nucynta.
  • Do not crush or break Nucynta tablets before taking them. Swallow whole.
  • You should avoid using this medicine if you are pregnant or planning to become pregnant.

Nucenta side effects

Side effects are a common treatment problem for any drug, and side effects are divided into:

  • Common side effects of tapentadol include:
    • Headache and feeling tired
    • Constipation, nausea and vomiting
    • stomach pain.
    • drowsiness, dizziness;

You can contact your doctor for advice about side effects, and you can report side effects to the FDA and the Food and Drug Administration.

  • Call your doctor at once if you have:
    • Shortness of breath, difficulty breathing, or shortness of breath.
    • Feeling like you might pass out.
    • Some agitation and feeling the heat.
    • Problems with balance or speech.
    • Dizziness or extreme drowsiness and confusion
    • convulsive fits;
    • Serotonin syndrome such as rapid heart rate, hallucinations, muscle stiffness, fever, tingling, nausea, and diarrhea.
    • Low cortisol levels that result in vomiting, nausea, loss of appetite, tiredness or weakness, and dizziness.
    • Asthenia, wasting syndrome, or chronic breathing disorders, especially in the elderly.
  • You should call the emergency medical department if you have:
    • Symptoms of an allergic reaction to tapentadol
    • Difficulty breathing and chest pain.
    • Rapid heart rate.
    • Swelling of the face, lips, throat and tongue.
    • Lip color changed to blue.
    • If you find it difficult to wake up.

Avoid taking opioid medicines such as Nucenta with alcohol or with medicines that slow your breathing or cause drowsiness.

Drugs that interact with Nucynta

Drugs that interact with Nucynta
Drugs that interact with Nucynta

Some medicines may interact with this medicine and may cause some serious side effects, including:

  • baclofen;
  • cyclobenzaprine.
  • Cymbalta (duloxetine).
  • Flexeril (cyclobenzaprine).
  • gabapentin;
  • levothyroxine;
  • lisinopril;
  • orphenadrine;
  • Lyrica (pregabalin).
  • Meloxicam.
  • metformin;
  • omeprazole;
  • oxycodone;
  • prednisone;
  • Synthroid (levothyroxine).
  • Amitriptyline.
  • tizanidine;
  • tramadol;
  • trazodone;
  • diazepam;
  • clonazepam;
  • Xanax (Alprazolam).
  • escitalopram;
  • fluoxetine;
  • paroxetine;
  • venlafaxine;
  • Vitamin D3 (cholecalciferol).

Read also: Abdominal MRI

Alternative medicine to Nucynta

There are many medicines equivalent to tapentadol in its action, such as:

  • palexia
  • Duovolt.
  • Tapal.
  • Tapcynta Tapcynta.

Nucynta is a prescription pain reliever for moderate to severe pain that is not controlled by non-opioid drugs. Be careful not to share Nucynta with anyone else to avoid misuse and addiction risks.