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Lodine is a non-steroidal anti-inflammatory drug that is widely used in our daily lives. Learn about the indications for use, the side effects of Lodine, the appropriate dosage of it, its effect on pregnant and lactating women, and the price of the drug in the market.


What is Lodine?

Lodine is a non-steroidal anti-inflammatory drug (NSAID), which works to reduce or reduce the hormones that cause pain in the body, as it acts as a powerful pain reliever and is frequently used to relieve and relieve pain that a patient may suffer from.

Generic name of the drug etodolac (etodolac).
Brand Names Lodine.
drug classification Of the class of non-steroidal anti-inflammatory drugs (NSAIDs).
Pharmaceutical Forms Oral solution/tablets/tablets.

Reasons for using Lodine

Reasons for using Lodine
Reasons for using Lodine

Lodine is a non-steroidal anti-inflammatory drug that has many uses and beneficial effects on the human body. It is a drug that works by reducing hormones that cause inflammation and severe physical pain. The main uses of this drug are:

  • Treatment of mild and moderate pain and its analgesia.
  • Rheumatoid arthritis treatment.
  • Treating and reducing osteoporosis.

There are also other indications for this medicine that are not included in this list.


Contraindications to the use of Lodine

In the event that the patient suffers from any chronic diseases or medical or surgical history, he must then inform the doctor of all these matters, as one of these diseases may prevent the patient from using this medicine. It is also important to address these contraindications and become familiar with them, as we include the following:

  • Hypersensitivity to this medicine or any of the compounds in its composition.
  • This medicine is contraindicated if the patient suffers from a heart attack.
  • Skin rash or changes and blurred vision.
  • Kidney problems.

Important tips before taking Lodine

Before taking any medication, it is important to know that adherence to the doctor’s advice and instructions is a duty of the patient to ensure his safety from any error that may occur as a result of negligence. The most important tips to follow before taking Lodine are:

  • Do not use this medicine before or after heart surgery as it may cause a heart attack or stroke.
  • Lodine should not be used if the patient is allergic to etodolac, has an asthma attack or is allergic to an NSAID.
  • Tell your doctor if you have heart disease, high blood pressure, diabetes, or if you are a smoker.
  • Tell the doctor if the patient is pregnant or wants to become pregnant.
  • Not approved for use by patients under 18 years of age.

pregnancy and breastfeeding

Some studies conducted on experimental animals during pregnancy have shown that taking this drug may cause abnormalities in the fetal skeleton, such as: (polydactyly, oligodactyly, overlap of fingers…). The use of non-steroidal anti-inflammatory drugs (NSAIDs) during the last months of pregnancy can cause significant adverse effects and may cause kidney problems and damage to the fetus.

Therefore, Lodine should be avoided during pregnancy and during labour, as the onset of labor may be delayed and its duration increased. While there are no results confirming the effect of the drug on the nursing mother or if it is excreted in breast milk, it is advised not to use this product during the breastfeeding period.


How to take Lodine

In order for the patient to take the medicine in the correct way, he must read the instructions attached to the back of the medicine package. It is also important to adhere to the dose prescribed by the doctor and to avoid crushing or breaking the tablet in your mouth, but rather swallow it whole. It may take up to two weeks for symptoms to improve.


Lodine Dosages

Lodine Dosages
Lodine Dosages

The appropriate dose varies for each patient according to his condition and health condition, so we attach great importance to the doctor’s advice about the correct dose during the medical visit. The appropriate dose can be roughly summarized as follows:

  • The required dose of Lodine for adult patients with osteoporosis:

It is 300 mg orally about 2-3 times a day or 400 mg to 500 mg twice a day. Where a maintenance dose of less than 600 mg per day is sufficient for prolonged use of this medicinal substance, while the maximum dose is 1000 mg per day only once.

The therapeutic response to ovine is excellent as immediate results can be seen in the patient within a week of treatment.

  • The usual dose of Lodine for rheumatoid arthritis:

The initial dose is 300 mg orally 2-3 times a day or 400-500 mg twice a day. A maintenance dose of less than 600 mg per day is also sufficient for long-term use. While the maximum dose is 100 mg orally once a day.

Improvement is noticeable within 2 weeks and dosage should be adjusted accordingly after a satisfactory response has been achieved.

  • Dosage of Lodine for rheumatoid arthritis in children aged 6-16 years with a weight of 20-30 kg:

The required dose is 400 mg orally once a day, weight from 31 to 45 kg: 60 mg orally once a day, and the dose varies according to the age of the patient until adulthood.

What do you do if you forget to take a dose?

If one day the patient forgets to take his dose on time, then the medicine must be taken as soon as he remembers it. If the patient forgets to take the medicine and the time for the next dose is approaching according to the dosing schedule, the missed dose should be skipped, paying attention not to take two doses at the same time.

What do you do if you take an overdose?

Taking an overdose of Etodolac causes side effects to the patient, including:

  • drowsiness.
  • Nausea and vomiting.
  • stomach bleeding
  • drug intoxication;

Therefore, seek immediate medical attention and call the Poison Help Line if you take too much Lodine.


Lodine side effects

Lodine side effects
Lodine side effects

This compound has many side effects like other medicines, so be careful when using this medicine and seek medical attention if any of the following symptoms or signs appear:

  • Allergic reactions to the drug, which it may cause in some patients.
  • face edema;
  • Runny or stuffy nose.
  • Difficulty breathing and fever.
  • Sore throat and burning eyes.
  • Skin pain and a red or purple rash with crusts and sores on the skin.
  • Chest pain spreading to the jaw or shoulder (signs of a heart attack).
  • Sudden numbness and weakness on one side of the body.
  • Shortness of breath, bloody stools, itching, nausea, stomach pain.
  • Flu-like symptoms.
  • Loss of appetite and dark urine.
  • Low red blood cell count.
  • Indigestion, diarrhea or constipation.

Drugs that interact with Lodine

Pharmacological sharing between a group of medicines and randomly without resorting to the doctor leads to the occurrence of many problems and side effects that may be bad for the patient’s health. The most important medicines not to be combined with Lodine are:

  • Antidepressants
  • cyclosporine;
  • lithium.
  • methotrexate;
  • warfarin;
  • Coumadin.
  • Jantoven.
  • Heart and blood pressure medications.
  • diuretics;

This list is not sufficient and does not include all drugs that interact with etodolac.


Alternative medicines for Lodine

Pain relief is not required to be relieved by using Lodine alone. Rather, the medication and analgesic prescribed to the patient varies according to his health and general condition. A patient who suffers from various chronic diseases can also make him have an anti-indication for the use of Lodine, including resorting to one of the alternative medicines for him to relieve his pain and solve his problem. Therefore, among the most important alternative medicines to Lodine, we can mention the following:

  • April.
  • Humira.
  • aspirin.
  • prednisone;
  • ibuprofen;
  • tramadol;
  • Meloxicam.
  • naproxen;
  • Tylenol.

Do not forget the importance of following the doctor’s advice during the medical consultation and adhere to his instructions about the most appropriate alternative for your case.


Loden price in local markets

The cost of Oral Lodine at a dose of 400 mg is about $576 for 30 tablets of the drug, the price of which varies depending on the pharmacy the patient visits. The rate is for cash-paying customers only and is not valid with insurance plans.

Read also: “Etopophos injection”


Frequently asked questions about lodine

Does lodine cause addiction?

No, Lodine is not addictive and is not controlled.


Lodine is a non-steroidal anti-inflammatory drug. It is used to relieve pain, however, it has severe side effects and many contraindications, so caution should be exercised during its use. Do not forget the importance of consulting your doctor about the appropriate dosage of the drug.